President Trump said on Monday that he has been taking hydroxychloroquine, an antimalarial drug whose effectiveness against the coronavirus is unproven, for about a week and a half as a preventive measure.

“All I can tell you is, so far I seem to be OK,” he said, explaining that he takes a daily pill. The White House physician said later that Mr. Trump had no symptoms and had regularly tested negative for the virus.

The Food and Drug Administration issued a safety warning in April about hydroxychloroquine and chloroquine, malaria prevention drugs that have been repeatedly promoted by Mr. Trump and widely used to treat virus patients despite the lack of evidence that they work.

The drugs can cause dangerous abnormalities in heart rhythm in virus patients, the F.D.A. warned, saying they should be used only in clinical trials or hospitals where patients can be closely monitored for heart problems.

Several doctors said they were alarmed that Mr. Trump was using the bully pulpit of the presidency to tell the public he takes a drug that has not been proven to be effective against the coronavirus, but which does have known risks.

Dr. Steven E. Nissen, the chief academic officer of the Miller Family Heart, Vascular & Thoracic Institute at the Cleveland Clinic, said he had treated patients who developed a life-threatening arrhythmia.

“This disorder can be lethal,” Dr. Nissen said. “My concern would be that the public not hear comments about the use of hydroxychloroquine and believe that taking this drug to prevent Covid-19 infection is without hazards.

“In fact, there are serious hazards.”

Early studies of hydroxychloroquine in the laboratory, which showed that the drug could block the virus from attacking cells, prompted enthusiasm. But the studies of the drug in humans have largely proved disappointing, and some have pointed to serious side effects in people with heart problems.

“I’m not going to get hurt by it,” said Mr. Trump, 73, explaining that he was making the disclosure in order to be transparent with Americans. “It has been around for 40 years for malaria, for lupus, for other things. I take it. Front-line workers take it. A lot of doctors take it.”

The New York Times

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